COCKAYNE SYNDROME LINKED TO ELEVATED R-LOOPS INDUCED BY STALLED RNA POLYMERASE II DURING TRANSCRIPTION ELONGATION

Cockayne Syndrome Linked to Elevated R-Loops Induced by Stalled RNA Polymerase II during Transcription Elongation

Abstract Mutations in the Cockayne Syndrome group B (CSB) gene cause cancer in mice, but premature aging and severe neurodevelopmental defects in humans.CSB, a Vanadium member of the SWI/SNF family of chromatin remodelers, plays diverse roles in regulating gene expression and transcription-coupled nucleotide excision repair (TC-NER); however, these

read more

Secure Communication With Energy-Harvesting Buffer-Aided Jammer

Information security and self-sustainability are crucial to resource-limited wireless networks.In this paper, we assess Battery the secrecy performance of the legitimate link without having eavesdropper’s channel state information (CSI) while considering an energy harvesting (EH) jammer with finite and infinite energy buffer sizes.The EH jam

read more